Diseño de una biotinta tipo hidrogel a base de polietilenglicol diacrilado con plasma rico en plaquetas, dirigida a la fabricación de apósitos para úlceras crónicas de pie diabético por bioimpresión 3D

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dc.contributor.apolounabSolarte David, Víctor Alfonso [Victor-Solarte-David]spa
dc.contributor.authorSolarte David, Víctor Alfonso
dc.contributor.cvlacSolarte David, Víctor Alfonso [1329391]spa
dc.contributor.googlescholarSolarte David, Víctor Alfonso [es&oi=ao]spa
dc.contributor.orcidSolarte David, Víctor Alfonso [0000-0002-9856-1484]spa
dc.coverage.campusUNAB Campus Bucaramangaspa
dc.coverage.spatialBucaramanga (Santander, Colombia)spa
dc.date.accessioned2023-08-23T12:31:47Z
dc.date.available2023-08-23T12:31:47Z
dc.date.issued2020
dc.description.abstractLa diabetes afecta a más de 463 millones de personas en el mundo, y se estima que dentro de 25 años más de 700 millones padecerán esta enfermedad. Entre las complicaciones más frecuentes están las úlceras crónicas de pie diabético (UCPD), y se estima que se presentarán en un cuarto de la población diabética a lo largo de su vida. Las UCPD, presentan un alto riesgo de infección convirtiéndose en la principal causa de amputaciones no traumáticas en el mundo, adicionalmente, es una enfermedad de alto costo para los sistemas de salud. En la actualidad, los tratamientos son efectivos solo en la mitad de las UCPD tratadas, lo que evidencia que los métodos terapéuticos tradicionales no son adecuados para todos los pacientes, adicionalmente, este tipo de úlceras presentan altas cantidades de metaloproteinasas (MPMs) lo que no permite la formación de matriz que lleve a la cicatrización del tejido.spa
dc.description.abstractenglishDiabetes affects more than 463 million people in the world, and it is estimated that within 25 years more than 700 million will suffer from this disease. Chronic diabetic foot ulcers (UCPD) are among the most frequent complications, and it is estimated that they will occur in a quarter of the diabetic population throughout their lives. The UCPD present a high risk of infection, becoming the main cause of non-traumatic amputations in the world, additionally, it is a high-cost disease for health systems. At present, the treatments are effective in only half of the UCPD treated, which shows that traditional therapeutic methods are not suitable for all patients, additionally, this type of ulcers have high amounts of metalloproteinases (MPMs), which is not allows the formation of matrix that leads to tissue healing.spa
dc.description.learningmodalityModalidad Presencialspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.instnameinstname:Universidad Autónoma de Bucaramanga - UNABspa
dc.identifier.reponamereponame:Repositorio Institucional UNABspa
dc.identifier.repourlrepourl:https://repository.unab.edu.cospa
dc.identifier.urihttp://hdl.handle.net/20.500.12749/21358
dc.language.isospaspa
dc.publisher.facultyFacultad Ciencias de la Saludspa
dc.publisher.grantorUniversidad Autónoma de Bucaramanga UNABspa
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dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.creativecommonsAtribución-NoComercial-SinDerivadas 2.5 Colombia*
dc.rights.localAbierto (Texto Completo)spa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/*
dc.subject.keywordsMetabolism disordersspa
dc.subject.keywordsPlatelet rich plasmaspa
dc.subject.keywordsBloodspa
dc.subject.keywordsThree-dimensional image in designspa
dc.subject.keywordsBioinkspa
dc.subject.keywordsDiabetic footspa
dc.subject.lembDiabetesspa
dc.subject.lembTrastornos del metabolismospa
dc.subject.lembPlasma rico en plaquetasspa
dc.subject.lembSangrespa
dc.subject.lembImagen tridimensional en diseñospa
dc.subject.proposalBiotintaspa
dc.subject.proposalPie diabéticospa
dc.titleDiseño de una biotinta tipo hidrogel a base de polietilenglicol diacrilado con plasma rico en plaquetas, dirigida a la fabricación de apósitos para úlceras crónicas de pie diabético por bioimpresión 3Dspa
dc.title.translatedDesign of a hydrogel-type bioink based on diacrylated polyethylene glycol with platelet-rich plasma, aimed at the manufacture of dressings for chronic diabetic foot ulcers by 3D bioprintingspa
dc.typeResearch reporteng
dc.type.coarhttp://purl.org/coar/resource_type/c_18ws
dc.type.coarversionhttp://purl.org/coar/version/c_ab4af688f83e57aaspa
dc.type.driverinfo:eu-repo/semantics/workingPaperspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.type.localInforme de investigaciónspa
dc.type.redcolhttp://purl.org/redcol/resource_type/IFIspa

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