Efectividad analgésica y seguridad de la radiofrecuencia combinada a baja temperatura del ganglio de gasser como tratamiento para neuralgia del trigémino

Vista sencilla de ítem
dc.contributor.advisorRangel Jaimes, German William
dc.contributor.advisorOrtega Agón, Karina Alejandra
dc.contributor.advisorGómez Garcés, Sonia Luz
dc.contributor.apolounabRangel Jaimes, German William [german-william-rangel-jaimes-2]spa
dc.contributor.apolounabOrtega Agon, Karina Alejandra [karina-alejandra-ortega-agon]spa
dc.contributor.apolounabGómez Garcés, Sonia Luz [sonia-luz-gómez-garcés]spa
dc.contributor.authorRangel Santos, Daniela
dc.contributor.cvlacRangel Santos, Daniela [1018487422]spa
dc.contributor.cvlacRangel Jaimes, German William [13922808]spa
dc.contributor.cvlacOrtega Agon, Karina Alejandra [1020734519]spa
dc.contributor.cvlacGómez Garcés, Sonia Luz [0001659600]spa
dc.contributor.orcidRangel Santos, Daniela [https://orcid.org/0000-0001-5397-793X]spa
dc.contributor.orcidRangel Jaimes, German William [0000-0002-7946-9906]spa
dc.contributor.orcidOrtega Agon, Karina Alejandra [0000-0001-6023-3760]spa
dc.contributor.orcidGómez Garcés, Sonia Luz [0000-0003-1865-2923]spa
dc.contributor.researchgroupSemilleros de Investigación UNABspa
dc.coverage.campusUNAB Campus Bucaramangaspa
dc.coverage.spatialFloridablanca (Santander, Colombia)spa
dc.coverage.temporal2022-2024spa
dc.date.accessioned2024-07-10T13:39:50Z
dc.date.available2024-07-10T13:39:50Z
dc.date.issued2024-06-25
dc.degree.nameEspecialista en Anestesiologíaspa
dc.description.abstractSe realizó un estudio analítico prospectivo el cual evaluó la efectividad y seguridad de la radiofrecuencia combinada a baja temperatura (60°C-65°C) en el ganglio de Gasser como tratamiento intervencionista analgésico en pacientes con neuralgia del trigémino de la Clínica del Dolor y Cuidado Paliativo ALIVIAR. Se incluyó un total de 60 pacientes quienes a criterio de su algólogo tratante fueron programados para realización del procedimiento, se excluyeron mujeres embarazadas y pacientes con imposibilidad de reportar la evaluación del dolor mediante las escalas planteadas. Se realizó un seguimiento a 6 meses, con seguimiento durante el día 1, día 7, día 30, día 60, día 90 y día 180 posterior al procedimiento. Se evaluó el delta del dolor utilizando la escala numérica del dolor (NRS), así como el cambio en el puntaje de dolor neuropático mediante el cuestionario DN4. Adicionalmente, se evaluó la presencia de complicaciones postprocedimiento a 180 días. El delta del dolor por NRS y el cambio en la media de puntaje de DN4 fueron estadísticamente significativos a cada momento del seguimiento. Ninguna complicación grave se mantuvo posterior al dia 7 de seguimiento. Como conclusión, se consideró que la radiofrecuencia combinada del ganglio de Gasser a baja temperatura es un procedimiento efectivo y seguro como tratamiento para la neuralgia del trigémino.spa
dc.description.abstractenglishA prospective analytical study was carried out to evaluate the effectiveness and safety of low temperature (60°C-65°C) combined radiofrequency in Gasser's ganglion as an interventional analgesic treatment in patients with trigeminal neuralgia at the ALIVIAR Pain and Palliative Care Clinic. A total of 60 patients were included who, at the discretion of their treating algologist, were scheduled for the procedure; pregnant women and patients unable to report pain assessment using the scales proposed were excluded. A 6-month follow-up was performed, with follow-up on day 1, day 7, day 30, day 60, day 90 and day 180 after the procedure. The pain delta was evaluated using the numerical pain scale (NRS), as well as the change in the neuropathic pain score using the DN4 questionnaire. Additionally, the presence of postprocedural complications at 180 days was assessed. The delta of pain by NRS and the change in mean DN4 score were statistically significant at each follow-up time point. No major complications remained after day 7 follow-up. In conclusion, combined low-temperature radiofrequency of Gasser's ganglion was considered to be an effective and safe procedure as a treatment for trigeminal neuralgia.spa
dc.description.degreelevelEspecializaciónspa
dc.description.learningmodalityModalidad Presencialspa
dc.description.tableofcontents1. PLANTEAMIENTO DEL PROBLEMA 2. PREGUNTA DE INVESTIGACIÓN 3. HIPÓTESIS INVESTIGATIVA 4. MARCO TEÓRICO Y ESTADO DEL ARTE 5. JUSTIFICACIÓN 6. OBJETIVOS 6.1. OBJETIVO GENERAL 6.2. OBJETIVOS ESPECÍFICOS 7. METODOLOGÍA 7.1. VARIABLES 7.2. PLAN DE ANÁLISIS ESTADÍSTICO 7.3. RESULTADOS ESPERADOS 7.4. FLUJOGRAMA DE MANEJO DEL PACIENTE 7.5. CRONOGRAMA DE ACTIVIDADES 8. CONSIDERACIONES ÉTICAS 9. RESULTADOS 10. ANÁLISIS Y DISCUSIÓN 11. CONCLUSIONES 12. ANEXOS 12.1. ANEXO 1 – CONSENTIMIENTO INFORMADO 12.2. ANEXO 2 – INSTRUMENTO DE RECOLECCIÓN 13. BIBLIOGRAFÍAspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.instnameinstname:Universidad Autónoma de Bucaramanga - UNABspa
dc.identifier.reponamereponame:Repositorio Institucional UNABspa
dc.identifier.repourlrepourl:https://repository.unab.edu.cospa
dc.identifier.urihttp://hdl.handle.net/20.500.12749/25415
dc.language.isospaspa
dc.publisher.facultyFacultad Ciencias de la Saludspa
dc.publisher.grantorUniversidad Autónoma de Bucaramanga UNABspa
dc.publisher.programEspecialización en Anestesiologíaspa
dc.publisher.programidEANE-1049
dc.relation.referencesBendtsen L, Zakrzewska J, Bruvik Heinskou T, Hodaie M, Roberto Lacerda Leal P, Nurmikko T, et al. Advances in diagnosis, classification, pathophysiology, and management of trigeminal neuralgia. Lancet Neurol [Internet]. 2020;19:784–96. Available from: www.thelancet.com/neurologyspa
dc.relation.referencesMaarbjerg S, di Stefano G, Bendtsen L, Cruccu G. Trigeminal neuralgia - Diagnosis and treatment. Vol. 37, Cephalalgia. SAGE Publications Ltd; 2017. p. 648–57.spa
dc.relation.referencesJones MR, Urits I, Ehrhardt KP, Cefalu JN, Kendrick JB, Park DJ, et al. A Comprehensive Review of Trigeminal Neuralgia. Vol. 23, Current Pain and Headache Reports. Current Medicine Group LLC 1; 2019.spa
dc.relation.referencesYadav Y, Nishtha Y, Sonjjay P, Vijay P, Shailendra R, Yatin K. Trigeminal neuralgia. Asian Journal of Neurosurgery [Internet]. 2017;12(4):585. Available from: http://www.asianjns.org/text.asp?2017/12/4/585/215788spa
dc.relation.referencesZakrzewska JM, Wu J, Mon-Williams M, Phillips N, Pavitt SH. Evaluating the impact of trigeminal neuralgia. Pain. 2017 Jun 1;158(6):1166–74.spa
dc.relation.referencesKoopman JSHA, Dieleman JP, Huygen FJ, de Mos M, Martin CGM, Sturkenboom MCJM. Incidence of facial pain in the general population. Pain. 2009 Dec 15;147(1–3):122–7.spa
dc.relation.referencesMaarbjerg S, Gozalov A, Olesen J, Bendtsen L. Trigeminal neuralgia-a prospective systematic study of clinical characteristics in 158 patients. Headache. 2014 Nov 1;54(10):1574–82spa
dc.relation.referencesLewis DW, Gozzo YF, Avner MT. The “other” primary headaches in children and adolescents. Vol. 33, Pediatric Neurology. 2005. p. 303–13.spa
dc.relation.referencesBendtsen L, Zakrzewska JM, Abbott J, Braschinsky M, di Stefano G, Donnet A, et al. European Academy of Neurology guideline on trigeminal neuralgia. Vol. 26, European Journal of Neurology. Blackwell Publishing Ltd; 2019. p. 831–49spa
dc.relation.referencesSiqueira SRDT, Alves B, Malpartida HMG, Teixeira MJ, Siqueira JTT. Abnormal expression of voltage-gated sodium channels Nav1.7, Nav1.3 and Nav1.8 in trigeminal neuralgia. Neuroscience. 2009 Dec 1;164(2):573–7.spa
dc.relation.referencesTanaka BS, Zhao P, Dib-Hajj FB, Morisset V, Tate S, Waxman SG, et al. A gain-of-function mutation in Nav1.6 in a case of trigeminal neuralgia. Molecular Medicine. 2016;22:338–48.spa
dc.relation.referencesVandenkerkhof EG, Stitt L, Clark AJ, Gordon A, Lynch M, Morley-Forster PK, et al. Sensitivity of the DN4 in Screening for Neuropathic Pain Syndromes. Clinical Journal of Pain. 2018;34(1):30–6.spa
dc.relation.referencesBouhassira D, Attal N, Alchaar H, Boureau F, Brochet B, Bruxelle J, et al. Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4). Pain. 2005;114(1–2):29–36.spa
dc.relation.referencesGuo J, Dong X, Zhao X. Treatment of trigeminal neuralgia by radiofrequency of the Gasserian ganglion. Reviews in the Neurosciences. 2016 Oct 1;27(7):739–43.spa
dc.relation.referencesVanneste T, van Lantschoot A, van Boxem K, van Zundert J. Pulsed radiofrequency in chronic pain. Vol. 30, Current Opinion in Anaesthesiology. Lippincott Williams and Wilkins; 2017. p. 577–82.spa
dc.relation.referencesFouad W. Management of trigeminal neuralgia by radiofrequency thermocoagulation. Alexandria Journal of Medicine. 2011 Mar 1;47(1):79–86.spa
dc.relation.referencesHong T, Ding Y, Yao P. Long-Term Efficacy and Complications of Radiofrequency Thermocoagulation at Different Temperatures for the Treatment of Trigeminal Neuralgia. Vol. 2020, Biochemistry Research International. Hindawi Limited; 2020.spa
dc.relation.referencesYitong J, Yuesong P, Hao R, Nan J, Fang Luo. Effectiveness and Safety of High-Voltage Pulsed Radiofrequency to Treat Patients with Primary Trigeminal Neuralgia: A Multicenter, Randomized, Double-Blind, Controlled Study Protocol. Pain Physician. 2018;21(1533–3159):469–81.spa
dc.relation.referencesJi N, Hospital BT, Luo F, Wang T, Shen Y, Meng L, et al. High Voltage Pulsed Radiofrequency for the Treatment of Refractory Neuralgia of the Infraorbital Nerve: A Prospective Double-Blinded Randomized Controlled Study. Pain Physician [Internet]. 2017;20:271–9. Available from: www.painphysicianjournal.comwww.painphysicianjournal.comspa
dc.relation.referencesWu H, Zhou J, Chen J, Gu Y, Shi L, Ni H. Therapeutic efficacy and safety of radiofrequency ablation for the treatment of trigeminal neuralgia: A systematic review and meta-analysis. Journal of Pain Research. 2019;12:423–41.spa
dc.relation.referencesCheol Chang M. Efficacy of Pulsed Radiofrequency Stimulation in Patients with Peripheral Neuropathic Pain: A Narrative Review [Internet]. Vol. 21, Narrative Review. 2018. Available from: www.painphysicianjournal.comspa
dc.relation.referencesFang L, Yitong J, Zheng Chen, Hao Ren. Observational Study The Effectiveness and Safety of 42°C Pulsed Radiofrequency Combined with 60°C Continuous Radiofrequency for Refractory Infraorbital Neuralgia: A Prospective Study [Internet]. 2019. Available from: www.painphysicianjournal.comspa
dc.relation.referencesAli Eissa AA, Reyad RM, Saleh EG, El-Saman A. The efficacy and safety of combined pulsed and conventional radiofrequency treatment of refractory cases of idiopathic trigeminal neuralgia: a retrospective study. Journal of Anesthesia. 2015 Oct 1;29(5):728–33spa
dc.relation.referencesShehata GA, Elawamy A, Abdalla E. Prospective Study Effects of Pulsed Versus Conventional Versus Combined Radiofrequency for the Treatment of Trigeminal Neuralgia: A Prospective Study. Pain Physician [Internet]. 2017;20:873–81. Available from: www.painphysicianjournal.comwww.painphysicianjournal.comspa
dc.relation.referencesZhou G, Ding Y, Li H, Hong T, Zhu Y, Yao P. Retrospective Study Combination of Pulsed Radiofrequency with Continuous Radiofrequency Thermocoagulation at Low Temperature Improves Efficacy and Safety in V2/V3 Primary Trigeminal Neuralgia. Pain Physician [Internet]. 2018;21(2150–1149):E545–53. Available from: www.painphysicianjournal.comspa
dc.relation.uriapolohttps://apolo.unab.edu.co/en/persons/german-william-rangel-jaimes-2spa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.creativecommonsAtribución-NoComercial-SinDerivadas 2.5 Colombia*
dc.rights.localAbierto (Texto Completo)spa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/*
dc.subject.keywordsAnesthesiologyspa
dc.subject.keywordsMedical sciencesspa
dc.subject.keywordsHealth sciencesspa
dc.subject.keywordsMedicinespa
dc.subject.keywordsTrigeminal neuralgiaspa
dc.subject.keywordsCombined radiofrequencyspa
dc.subject.keywordsFacial painspa
dc.subject.keywordsInterventional painspa
dc.subject.keywordsNeuropathic painspa
dc.subject.keywordsPain medicinespa
dc.subject.keywordsPain (Treatment)spa
dc.subject.keywordsClinical pharmacologyspa
dc.subject.lembAnestesiologíaspa
dc.subject.lembCiencias médicasspa
dc.subject.lembMedicinaspa
dc.subject.lembNeuralgiaspa
dc.subject.lembMedicina del dolorspa
dc.subject.lembDolor (Tratamiento)spa
dc.subject.lembAnalgesiaspa
dc.subject.lembFarmacología clínicaspa
dc.subject.proposalCiencias de la saludspa
dc.subject.proposalDolor facialspa
dc.subject.proposalNeuralgia del trigéminospa
dc.subject.proposalDolor neuropáticospa
dc.subject.proposalRadiofrecuencia combinadaspa
dc.subject.proposalIntervencionismo analgésicospa
dc.titleEfectividad analgésica y seguridad de la radiofrecuencia combinada a baja temperatura del ganglio de gasser como tratamiento para neuralgia del trigéminospa
dc.title.translatedAnalgesic effectiveness and safety of combined low-temperature radiofrequency of the gasser ganglion as a treatment for trigeminal neuralgiaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_bdcc
dc.type.coarversionhttp://purl.org/coar/version/c_b1a7d7d4d402bccespa
dc.type.driverinfo:eu-repo/semantics/masterThesis
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersion
dc.type.localTesisspa
dc.type.redcolhttp://purl.org/redcol/resource_type/TM

Archivos

Bloque original

Mostrando 1 - 2 de 2
Miniatura
Nombre:
Tesis.pdf
Tamaño:
829 KB
Formato:
Adobe Portable Document Format
Descripción:
Tesis
Descargar
Miniatura
Nombre:
Licencia.pdf
Tamaño:
273.34 KB
Formato:
Adobe Portable Document Format
Descripción:
Licencia
Descargar

Bloque de licencias

Mostrando 1 - 1 de 1
Miniatura
Nombre:
license.txt
Tamaño:
829 B
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar

Colecciones

Especialización en Anestesiología