Revisión documental sobre el uso de sustancias psicodélicas en la psicoterapia

dc.contributor.advisorOrtega Ortiz, Martha Eugenia
dc.contributor.apolounabOrtega Ortiz, Martha Eugenia [martha-eugenia-ortega-ortiz]spa
dc.contributor.authorGarcía Duran, Idy Mariana
dc.contributor.authorClaros Pinilla, Angie Carolina
dc.contributor.authorCabezas Ramírez, Sebastián Eduardo
dc.contributor.cvlacOrtega Ortiz, Martha Eugenia [0000194905]spa
dc.contributor.orcidOrtega Ortiz, Martha Eugenia [0000-0002-2396-4449]spa
dc.contributor.researchgroupGrupo de Investigación en Calidad de Vida y Salud Públicaspa
dc.coverage.campusUNAB Campus Bucaramangaspa
dc.coverage.spatialColombiaspa
dc.coverage.temporalFebrero a noviembre de 2024spa
dc.date.accessioned2024-12-02T16:14:01Z
dc.date.available2024-12-02T16:14:01Z
dc.date.issued2024-11-22
dc.degree.namePsicólogospa
dc.description.abstractEsta revisión documental examina el uso de sustancias psicodélicas en la psicoterapia, analizando publicaciones científicas sobre sus aplicaciones terapéuticas, mecanismos de acción y protocolos de implementación. La investigación utiliza un diseño cualitativo de tipo documental, empleando fichas bibliográficas como instrumento principal para la recolección y análisis de datos. Los resultados evidencian que los psicodélicos clásicos (LSD, DMT, psilocibina) y el MDMA muestran eficacia terapéutica significativa en el tratamiento de diversos trastornos mentales, particularmente en ansiedad, depresión resistente al tratamiento y TEPT. Los mecanismos de acción identificados involucran principalmente la activación de receptores 5-HT2A, generando cambios en la conectividad cerebral y mayor flexibilidad cognitiva. También, que la eficacia terapéutica depende de la integración de estas sustancias dentro de un protocolo psicoterapéutico estructurado, con fases de preparación, experiencia e integración. A su vez, se identifican vacíos significativos en la investigación, especialmente en el tratamiento de trastornos de la personalidad y efectos del consumo a largo plazo. Se concluye que, aunque los resultados preliminares son prometedores, se requieren estudios más amplios, controlados y longitudinales para establecer protocolos estandarizados y comprender mejor los mecanismos neurobiológicos subyacentes.spa
dc.description.abstractenglishThis documentary review examines the use of psychedelic substances in psychotherapy by analyzing scientific publications on their therapeutic applications, mechanisms of action, and implementation protocols. The research employs a qualitative documentary design, using bibliographic records as the primary instrument for data collection and analysis. Results show that classical psychedelics (LSD, DMT, psilocybin) and MDMA demonstrate significant therapeutic efficacy in treating various mental disorders, particularly anxiety, treatment-resistant depression, and PTSD. The identified mechanisms of action primarily involve the activation of 5-HT2A receptors, generating changes in brain connectivity and increased cognitive flexibility. The research also indicates that therapeutic efficacy depends on integrating these substances within a structured psychotherapeutic protocol, including preparation, experience, and integration phases. Additionally, significant research gaps were identified, especially regarding the treatment of personality disorders and long-term consumption effects. The study concludes that while preliminary results are promising, more extensive, controlled, and longitudinal studies are needed to establish standardized protocols and better understand the underlying neurobiological mechanisms.spa
dc.description.degreelevelPregradospa
dc.description.learningmodalityModalidad Presencialspa
dc.description.tableofcontentsIntroducción....................................................................................................8 Planteamiento del problema............................................................................... 10 Justificación..................................................................................................14 Objetivos......................................................................................................17 Objetivo general.....................................................................................17 Objetivos específicos...............................................................................17 Antecedentes.................................................................................................17 Internacionales......................................................................................18 Nacionales...........................................................................................20 Regional..............................................................................................23 Marco conceptual............................................................................................23 Psicodélicos..........................................................................................23 Historia de los psicodélicos...............................................................23 Definición..................................................................................25 Psilocibina.........................................................................26 Dietilamida del ácido lisérgico (LSD).........................................26 Ayahuasca.........................................................................26 Dimetiltriptamina (DMT).......................................................27 3.4-Metilenedioximetanfetamina (MDMA)..................................28 Efectos de los psicodélicos...............................................................29 Usos de los psicodélicos..................................................................34 Experiencias místicas de los psicodélicos..............................................35 Psicoterapia..........................................................................................38 Psicoterapia tradicional...................................................................38 Psicoterapia con psicodélicos............................................................39 Psicodélicos y trastornos clínicos..............................................40 Trastorno obsesivo compulsivo (TOC)...............................40 Trastorno de estrés postraumático (TEPT)...........................41 Depresión.................................................................42 Ansiedad..................................................................43 Adicciones................................................................44 Trastorno de la conducta alimentaria ................................45 Marco metodológico........................................................................................45 Tipo de investigación..............................................................................45 Diseño de investigación...........................................................................47 Estrategias o instrumentos........................................................................47 Participantes y criterios de elección.............................................................50 Procedimiento.......................................................................................51 Consideraciones éticas.............................................................................52 Plan de análisis de resultados..............................................................................52 Cronograma...................................................................................................54 Resultados....................................................................................................55 Discusión......................................................................................................67 Conclusiones.................................................................................................78 Recomendaciones............................................................................................79 Apéndices.....................................................................................................80 Referencias bibliográficas..................................................................................148spa
dc.format.mimetypeapplication/pdfspa
dc.identifier.instnameinstname:Universidad Autónoma de Bucaramanga - UNABspa
dc.identifier.reponamereponame:Repositorio Institucional UNABspa
dc.identifier.repourlrepourl:https://repository.unab.edu.cospa
dc.identifier.urihttp://hdl.handle.net/20.500.12749/27624
dc.language.isospaspa
dc.publisher.facultyFacultad Ciencias de la Saludspa
dc.publisher.grantorUniversidad Autónoma de Bucaramanga UNABspa
dc.publisher.programPregrado Psicologíaspa
dc.publisher.programidPSI-265spa
dc.relation.referencesAday, J. S., Carpenter, R. W., & Holden, J. E. (2019). Un ensayo aleatorizado de psilocibina para el trastorno de estrés postraumático en veteranos militares. Revista de Psicofarmacología, 33(9), 1063-1071.spa
dc.relation.referencesAguirre, O. D., Vivas, J. I., & Velasco, R. (2015). Psicodélicos: Perspectivas Clínicas y Neuropsicológicas en el Estudio de las Experiencias Cumbre. Cultura: Lima (Perú), (29), 187-218.spa
dc.relation.referencesAlcohol and Drug Foundation. (7 de diciembre de 2023). What is DMT. https://adf.org.au/drug-facts/dmt/spa
dc.relation.referencesAmerican Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Arlington, VA: American Psychiatric Publishing.spa
dc.relation.referencesAmerican Psychological Association. (2017). Ethical principles of psychologists and code of conduct. Recuperado de https://www.apa.org/ethics/code/spa
dc.relation.referencesAzmoodeh, K., Thomas, E & Kamboj, S. (2022). Meditation Trips: A Thematic Analysis of the Combined Naturalistic Use of Psychedelics With Meditation Practices. Experimental and Clinical Psychopharmacology. 2023, Vol. 31, No. 3, 756–767 ISSN: 1064-1297 https://doi.org/10.1037/pha0000617spa
dc.relation.referencesBadilla, B., Badilla, S., Martínez Herrera, M., Quirce Balma, C. M., & Rodríguez, J. M. (2010). The Hallucinogens: their History, Anthropology, Chemistry and Pharmacology. [Los alucinógenos: su historia, antropología, química y farmacología]. Revista no especificada.spa
dc.relation.referencesBaggott MJ, Coyle JR, Siegrist JD, Garrison KJ, Galloway GP, Mendelson JE. Effects of 3,4-methylenedioxymethamphetamine on socioemotional feelings, authenticity, and autobiographical disclosure in healthy volunteers in a controlled setting. J Psychopharmacol. 2016 Apr;30(4):378-87. doi: 10.1177/0269881115626348. Epub 2016 Feb 15. PMID: 26880224.spa
dc.relation.referencesBalu, D. T., & Lucki, I. (2009). Adult hippocampal neurogenesis: its role in anxiety and depression. Molecular Psychiatry, 14(4), 355–362. https://doi.org/10.1038/mp.2009.21spa
dc.relation.referencesBanks, M. I., Dunne, J. D., Hutson, P. R., Krause, B. M., Lennertz, R. C., Nicholas, C. R., Raison, C. L., Riedner, B. A., Roseman, L., Sauder, C. J., Smith, R. F., & Wenthur, C. J. (2024). Co-administration of midazolam and psilocybin: Differential effects on subjective quality versus memory of the psychedelic experience. Neuropsychopharmacology. https://doi.org/10.1038/s41386-023-01626-zspa
dc.relation.referencesBarba, T., Kettner, H., Radu, C. et al. Psychedelics and sexual functioning: a mixed-methods study. Sci Rep 14, 2181 (2024). https://doi.org/10.1038/s41598-023-49817-4spa
dc.relation.referencesBarba T, Buehler S, Kettner H, Radu C, Cunha BG, Nutt DJ, Erritzoe D, Roseman L, Carhart-Harris R. Effects of psilocybin versus escitalopram on rumination and thought suppression in depression. BJPsych Open. 2022 Sep 6;8(5):e163. doi: 10.1192/bjo.2022.565. PMID: 36065128; PMCID: PMC9534928.spa
dc.relation.referencesBarker, S. A., McIlhenny, E. H., & Strassman, R. (2012). A critical review of reports of endogenous psychedelic N, N-dimethyltryptamines in humans: 1955-2010. Drug Testing and Analysis, 4(7-8), 617-635. https://doi.org/10.1002/dta.422spa
dc.relation.referencesBarnett, B. S., Srivastava, E. D., Linas, B. S., & Gao, F. (2021). The road ahead for psychedelic health worker education and credentialing. Harm Reduction Journal, 18(1), 1-6. https://doi.org/10.1186/s12954-021-00589-0spa
dc.relation.referencesBarret, F., Johnson, M & Griffiths, R. (2015). Validation of the revised Mystical Experience Questionnaire in experimental sessions with psilocybin. J Psychopharmacol. 2015 November; 29(11): 1182–1190. doi:10.1177/0269881115609019spa
dc.relation.referencesBimonte, G. (2022). Psicología transpersonal y psicodélicos. Colibri. https://www.colibri.udelar.edu.uy/jspui/bitstream/20.500.12008/36278/1/psicologia_transpersonal _y_psicodelicos_tfg_gonzalo_bimonte.pdfspa
dc.relation.referencesBogenschutz, M. P., & Johnson, M. W. (2016). Classic hallucinogens in the treatment of addictions. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 64, 250-258.spa
dc.relation.referencesBogenschutz, M. P. y Johnson, M. W. (2016). Terapia asistida por psilocibina clásica para el trastorno de ansiedad asociado con enfermedad terminal. En Psicodélicos, terapia y consejería (pp. 92-107). Multidisciplinary Association for Psychedelic Studies.spa
dc.relation.referencesBogenschutz, M. P., Forcehimes, A. A., Pommy, J. A., Wilcox, C. E., Barbosa, P. C. R., & Strassman, R. J. (2015). Psilocybin-assisted treatment for alcohol dependence: A proof-of-concept study. Journal of Psychopharmacology, 29(3), 289-299. http://www.en.psilosophy.info/pdf/psilocybin_assisted_treatment_for_alcohol_dependence_a_pro of_of_concept_study_(psilosophy.info).pdfspa
dc.relation.referencesBogenschutz, M. P., Ross, S., Bhatt, S., Baron, T., Forcehimes, A. A., Laska, E., Mennenga, S. E., O'Donnell, K., Owens, L. T., Podrebarac, S., Rotrosen, J., Tonigan, J. S., & Worth, L. (2022). Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use Disorder: A Randomized Clinical Trial. JAMA psychiatry. Vol 79(10), 953–962. https://doi.org/10.1001/jamapsychiatry.2022.2096spa
dc.relation.referencesBogenschutz, M. P., Ross, S., Bhatt, S., Chen, C. Y., Wall, M. B., Pommy, J. M., ... & Johnson, M. W. (2022). Un ensayo clínico aleatorizado de psilocibina para el trastorno por uso de alcohol. JAMA Psychiatry, 79(11), 1097-1105.spa
dc.relation.referencesBonnelle V, Smith WJ, Mason NL, Cavarra M, Kryskow P, Kuypers KP, Ramaekers JG, Feilding A. Analgesic potential of macrodoses and microdoses of classical psychedelics in chronic pain sufferers: a population survey. Br J Pain. 2022 Dec;16(6):619-631. doi: 10.1177/20494637221114962. Epub 2022 Jul 14. PMID: 36452124; PMCID: PMC9703241.spa
dc.relation.referencesBorissova, A., Ferguson, B., Wall, M., Morgan, C., Carhart-Harris, R., Bolstridge, M., Williams, T., Feilding, A., Murphy, K., Tyacke, R., Erritzoe, D., Stewart, L., Wolff, K., Nutt, D., Curran, H y Lawn, W. (2021). Acute effects of MDMA on trust, cooperative behavior and empathy: A double-blind, placebo-controlled experiment. J Psychopharmacol. 2021 May;35(5):547-555. doi: 10.1177/0269881120926673. Epub 2020 Jun 15.spa
dc.relation.referencesBouso, J. C., González, D., Fondevila, S., Cutchet, M., Fernández, X., Ribeiro Barbosa, P. C., Alcázar-Córcoles, M. Á., Araújo, W. S., Barbanoj, M. J., Fábregas, J. M., & Riba, J. (2012). Personality, psychopathology, life attitudes and neuropsychological performance among ritual users of ayahuasca: A longitudinal study. PLoS ONE, 7(8), e42421. https://doi.org/10.1371/journal.pone.0042421spa
dc.relation.referencesBouso, J. C., & Sánchez-Avilés, C. (2020). Ayahuasca y otras plantas de poder: Perspectivas multidisciplinarias. Editorial Catalonia.spa
dc.relation.referencesBreeksema, J.J., Niemeijer, A.R., Krediet, E. et al. Psychedelic Treatments for Psychiatric Disorders: A Systematic Review and Thematic Synthesis of Patient Experiences in Qualitative Studies. CNS Drugs Vol 34, 925–946 (2020). https://doi.org/10.1007/s40263-020-00748-yspa
dc.relation.referencesCalder, A.E., Hasler, G. Towards an understanding of psychedelic-induced neuroplasticity. Neuropsychopharmacol. Vol 48, 104–112 (2023). https://doi.org/10.1038/s41386-022-01389-zspa
dc.relation.referencesCalder, A.; Mock, S.; Friedli, N.; Pasi, P.; Hasler, G. (2023). Psychedelics in the treatment of eating disorders: Rationale and potential mechanisms. European Neuropsychopharmacology, Vol 75, Pages 1-14, ISSN 0924-977X, https://doi.org/10.1016/j.euroneuro.2023.05.008. (https://www.sciencedirect.com/science/article/pii/S0924977X23001098).spa
dc.relation.referencesCallaway, J. C. (2005). A Theoretical Explanation for Attending Mental Imagery During the Ethnogenic Trance State. Journal of Psychoactive Drugs, 37(4), 409–415. https://doi.org/10.1080/02791072.2005.10399819spa
dc.relation.referencesCarbonaro, T. M. y Gatch, M. B. (2021). Neurofarmacología de la N, N-dimetiltriptamina. Avances en farmacología y toxicología, 87, 1-31.spa
dc.relation.referencesCarbonaro, T. M., Bradstreet, M. P., Barrett, F. S., MacLean, K. A., Jesse, R., Johnson, M. W., & Griffiths, R. R. (2016). Survey study of challenging experiences after ingesting psilocybin mushrooms: Acute and enduring positive and negative consequences. Journal of psychopharmacology (Oxford, England), 30(12), 1268–1278. https://doi.org/10.1177/0269881116662634spa
dc.relation.referencesCarhart-Harris, R. L., Bolstridge, M., Rucker, J., Day, C. M., Erritzoe, D., Kaelen, M., ... & Taylor, D. (2016). Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study. The Lancet Psychiatry, 3(7), 619-627. https://doi.org/10.1016/S2215-0366(16)30065-7spa
dc.relation.referencesCarhart-Harris, R. L., Feilding, A., Kaelen, M., Lebedev, A. V., Lovden, M., Nilsson, J., & Nutt, D. J. (2016). LSD-induced entropic brain activity predicts subsequent personality change. Human Brain Mapping, 37(9), 3203-3213. https://doi.org/10.1002/hbm.23234spa
dc.relation.referencesCarhart-Harris, R. L., & Friston, K. J. (2019). REBUS and the anarchic brain: Toward a unified model of the brain action of psychedelics. Pharmacological Reviews, 71(3), 316-344. https://doi.org/10.1124/pr.118.017160spa
dc.relation.referencesCarhart-Harris, R. L., & Goodwin, G. M. (2017). The therapeutic potential of psychedelic drugs: Past, present, and future. Neuropsychopharmacology, 42(11), 2105–2113. https://doi.org/10.1038/npp.2017.84spa
dc.relation.referencesCarhart-Harris, R. L., Kaelen, M., Whalley, M. G., Bolstridge, M., Feilding, A., & Nutt, D. J. (2015). LSD enhances suggestibility in healthy volunteers. Psychopharmacology, 232(4), 785-794. https://doi.org/10.1007/s00213-014-3714-zspa
dc.relation.referencesCarhart-Harris, R. L., Leech, R., Hellyer, P. J., Shanahan, M., Feilding, A., Tagliazucchi, E., ... & Nutt, D. (2014). The entropic brain: A theory of conscious states informed by neuroimaging research with psychedelic drugs. Frontiers in Human Neuroscience, 8, 20. https://doi.org/10.3389/fnhum.2014.00020spa
dc.relation.referencesCarhart-Harris, R., & Nutt, D. (2017). Psicodélicos y terapia asistida por psicodélicos para enfermedades mentales: revisión y perspectivas. Revista de Neurociencia, 45(1), 66-79.spa
dc.relation.referencesCarhart-Harris, R. L., & Nutt, D. J. (2017). Serotonin and brain function: A tale of two receptors. Journal of Psychopharmacology, 31(9), 1091-1120. https://doi.org/10.1177/0269881117725915spa
dc.relation.referencesCatlow, B. J., Song, S., Paredes, D. A., Kirstein, C. L., & Sanchez-Ramos, J. (2013). Effects of psilocybin on hippocampal neurogenesis and extinction of trace fear conditioning. Experimental brain research, 228(4), 481–491. https://doi.org/10.1007/s00221-013-3579-0spa
dc.relation.referencesChaparro Díaz, F. (2022). Hacer de la visión una práctica: Procesos de integración de experiencias psicodélicas y tensiones alrededor de la experimentación y expansión del uso de psicodélicos [Tesis de grado, Universidad Externado de Colombia]. Repositorio Institucional.https://bdigital.uexternado.edu.co/server/api/core/bitstreams/056ff82e-2c85-4031-97 67-a4900a97e19a/contentspa
dc.relation.referencesChávez, E., Chávez, C & Zuquitana, J. (2020). Revisión bibliográfica de la ayahuasca y su uso terapéutico. Revista Peruana de Medicina Integrativa. 2020; 5(3): 118-23 https://rpmi.pe/index.php/rpmi/article/view/251spa
dc.relation.referencesCipriani, A., Furukawa, T. A., Salanti, G., Chaimani, A., Atkinson, L. Z., Ogawa, Y., ... & Geddes, J. R. (2018). Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: A systematic review and network meta-analysis. The Lancet, 391(10128), 1357-1366. https://doi.org/10.1016/S0140-6736(17)32802-7spa
dc.relation.referencesCole, J. C., & Sumnall, H. R. (2003). Adulterants in illicit drug markets. Nova Publishers.spa
dc.relation.referencesComas-Díaz, L. (2012). Multidimensional reality: Race, ethnicity, and connectedness in therapeutic encounters. Psychoanalytic Dialogues, 22(4), 393–407. https://doi.org/10.1080/10481885.2012.679604spa
dc.relation.referencesCórdoba Barreneche, M., Grisales Gómez, J., Iguarán Agudelo, S., & Rincones Pérez, J. (2021). Psicodélicos en el Tratamiento de la Depresión: una Revisión Sobre Eficacia y Seguridad [Tesis de pregrado, Facultad de Psicología]. Repositorio Institucional CES. https://repository.ces.edu.co/bitstream/handle/10946/5644/Psicod%c3%a9licos%20en%20el%20 Tratamiento%20de%20la%20Depresi%c3%b3n%3a%20una%20Revisi%c3%b3n%20Sobre%20 Eficacia%20y%20Seguridad?sequence=7&isAllowed=yspa
dc.relation.referencesCorrea, L. (2023). Estigma social y uso de psicodélicos en Medellín, Colombia. [Tesis para optar al título de magíster en Culturas y Droga]. Repositorio Digital Universidad de Caldas. https://repositorio.ucaldas.edu.co/handle/ucaldas/19788spa
dc.relation.referencesCornelius, C., Chong, D., Ayub, S., Brown, T y Shao, W. (2017). A Physician's Attempt to Self-Medicate Bipolar Depression with N,N-Dimethyltryptamine (DMT). J Psychoactive Drugs. 2017 Sep-Oct;49(4):294-296. doi: 10.1080/02791072.2017.1344898. Epub 2017 Jul 7.spa
dc.relation.referencesDa Costa SC, Oesterle T, Rummans TA, Richelson E, Gold M. Psychedelic drugs for psychiatric disorders. J Neurol Sci. 2022 Sep 15;440:120332. doi: 10.1016/j.jns.2022.120332. Epub 2022 Jul 5. PMID: 35841696.spa
dc.relation.referencesDanforth AL, Grob CS, Struble C, Feduccia AA, Walker N, Jerome L, Yazar-Klosinski B, Emerson A. Reduction in social anxiety after MDMA-assisted psychotherapy with autistic adults: a randomized, double-blind, placebo-controlled pilot study. Psychopharmacology (Berl). 2018 Nov;235(11):3137-3148. doi: 10.1007/s00213-018-5010-9. Epub 2018 Sep 8. PMID: 30196397; PMCID: PMC6208958.spa
dc.relation.referencesDavis, A. K., Barrett, F. S., Gukasyan, N., Hunt, C., Soskin, D. P., & Griffiths, R. R. (2023). Un ensayo clínico aleatorizado de LSD para la depresión mayor. Revista de Psicofarmacología, 37(1), 1-15.spa
dc.relation.referencesDavis, A. K., Barrett, F. S., May, D. G., Cosimano, M. P., Sepede, N. D., Johnson, M. W., ... & Griffiths, R. R. (2021). Effects of psilocybin-assisted therapy on major depressive disorder. JAMA psychiatry, 78(5), 481-489. https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2772630spa
dc.relation.referencesDavis, A.K.; Barrett, F.S.; May, D.G.; et al. (2021). Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder: A Randomized Clinical Trial. JAMA Psychiatry. Vol 78(5):481–489. doi:10.1001/jamapsychiatry.2020.3285spa
dc.relation.referencesde Veen, B. T. H., Schellekens, A. F. A., Verheij, M. M. M., & Homberg, J. R. (2017). Psilocybin for treating substance use disorders? Expert Review of Neurotherapeutics, 17(2), 203-212. https://www.tandfonline.com/doi/full/10.1080/14737175.2016.1220834spa
dc.relation.referencesDavis AK, Clifton JM, Weaver EG, Hurwitz ES, Johnson MW, Griffiths RR. Survey of entity encounter experiences occasioned by inhaled N,N-dimethyltryptamine: Phenomenology, interpretation, and enduring effects. J Psychopharmacol. 2020 Sep;34(9):1008-1020. doi: 10.1177/0269881120916143. Epub 2020 Apr 28. PMID: 32345112.spa
dc.relation.referencesDepartamento de Asuntos Económicos y Sociales de las Naciones Unidas. Salud mental y desarrollo [Internet]. Nueva York: Naciones Unidas [Consultado el 20 de diciembre del 2021]. Disponible en: https://www.un.org/development/desa/ disabilities/issues/mental-health-and-development.htmlspa
dc.relation.referencesDoblin, R. (2021). MDMA-asistida por terapia para el TEPT: un nuevo paradigma en la psicoterapia. Revista de Psicofarmacología, 32(1), 21-28.spa
dc.relation.referencesDomínguez-Clavé E, Soler J, Pascual JC, Elices M, Franquesa A, Valle M, Alvarez E, Riba J. Ayahuasca improves emotion dysregulation in a community sample and in individuals with borderline-like traits. Psychopharmacology (Berl). 2019 Feb;236(2):573-580. doi: 10.1007/s00213-018-5085-3. Epub 2018 Nov 7. PMID: 30406413.spa
dc.relation.referencesDos Santos, R. G. (2016). Psicoterapia asistida con ayahuasca: un enfoque terapéutico polivagal integrado. En B. C. Labate y C. Cavnar (Eds.), Psicodélicos, terapia y consejería (pp. 130–153). Multidisciplinary Association for Psychedelic Studies.spa
dc.relation.referencesDos Santos, R. G., Bouso, J. C., Rocha, J. M., Rossi, G. N., & Hallak, J. E. (2017). Ayahuasca, dimethyltryptamine, and psychosis: a systematic review of human studies. Therapeutic Advances in Psychopharmacology, 7(4), 141-157. https://doi.org/10.1177/2045125316689030spa
dc.relation.referencesDos Santos, R. G., Osório, F. L., Crippa, J. A. S., Riba, J., Zuardi, A. W., & Hallak, J. E. C. (2016). Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): A systematic review of clinical trials published in the last 25 years. Therapeutic Advances in Psychopharmacology, 6(3), 193–213. https://doi.org/10.1177/2045125316638008spa
dc.relation.referencesD’Souza, D.C., Syed, S.A., Flynn, L.T. et al. Exploratory study of the dose-related safety, tolerability, and efficacy of dimethyltryptamine (DMT) in healthy volunteers and major depressive disorder. Neuropsychopharmacol. 47, 1854–1862 (2022). https://doi.org/10.1038/s41386-022-01344-yspa
dc.relation.referencesEscohotado, A. (1998). Historia general de las drogas. Espasa Calpe.spa
dc.relation.referencesFadiman, J., & Korb, S. (2019). Might microdosing psychedelics be safe and beneficial? An initial exploration. Journal of Psychoactive Drugs, 51(2), 118-122.spa
dc.relation.referencesFauvel, B., Strika-Bruneau, L. y Piolino, P. (2021). Changes in Self-rumination and Self-compassion Mediate the Effect of Psychedelic Experiences on Decreases in Depression, Anxiety, and Stress. Psychology of Consciousness: Theory, Research, and Practice, Vol. 10, No. 1, 88–102. https://doi.org/10.1037/cns0000283spa
dc.relation.referencesFeldman, R. (2009). Psicología con aplicaciones en países de habla hispana. McGrawHill. https://es.slideshare.net/ronnypradovasquez/robert-s-feldmanpsicologia-con-aplicaciones-en-pais es-de-habla-hispanapdfspa
dc.relation.referencesForstmann, M y Sagioglou, C. (2021). New Insights Into the Clinical and Nonclinical Effects of Psychedelic Substances. European Psychologist (2022), 27(4), 291–301. https://doi.org/10.1027/1016-9040/a000447spa
dc.relation.referencesFrecska, E., Bokor, P., & Winkelman, M. (2016). The Therapeutic Potentials of Ayahuasca: Possible Effects against Various Diseases of Civilization. Frontiers in Pharmacology, 7. https://doi.org/10.3389/fphar.2016.00035spa
dc.relation.referencesFreudenmann, R. W., Oxler, F., & Bernschneider-Reif, S. (2006). The origin of MDMA (ecstasy) revisited: The true story reconstructed from the original documents. Addiction, 101(9), 1241-1245. https://doi.org/10.1111/j.1360-0443.2006.01511.xspa
dc.relation.referencesGarcía-Romeu, A., & Richards, W. A. (2018). Current perspectives on psychedelic therapy: Use of serotonergic hallucinogens in clinical interventions. International Review of Psychiatry, 30(4), 291–316. https://doi.org/10.1080/09540261.2018.1486258spa
dc.relation.referencesGarcía-Romeu, A., Griffiths, R. R., & Johnson, M. W. (2016). Psilocybin-occasioned mystical experiences in the treatment of tobacco addiction. Current Drug Abuse Reviews, 9(1), 30-35. https://akjournals.com/view/journals/2054/7/1/article-p18.xmlspa
dc.relation.referencesGasser, P., Kirchner, K., & Passie, T. (2015). LSD-assisted psychotherapy for anxiety associated with a life-threatening disease: A qualitative study of acute and sustained subjective effects. Journal of Psychopharmacology, 29(1), 57-68. https://doi.org/10.1177/0269881114555249spa
dc.relation.referencesGraziosi, M., Hinkle, J. T., Nayak, S. M., & Yaden, D. B. (2023). Adverse events in studies of classic psychedelics: A systematic review and meta-analysis. Journal of Psychopharmacology. https://doi.org/10.1177/02698811231203037spa
dc.relation.referencesGreenberg, P. E., Fournier, A. A., Sisitsky, T., Pike, C. T., & Kessler, R. C. (2015). The economic burden of adults with major depressive disorder in the United States (2005 and 2010). The Journal of Clinical Psychiatry, 76(2), 155-162. https://doi.org/10.4088/JCP.14m09298spa
dc.relation.referencesGreen, A. R., Mechan, A. O., Elliott, J. M., O'Shea, E., & Colado, M. I. (2003). The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"). Pharmacological Reviews, 55(3), 463-508. https://doi.org/10.1124/pr.55.3.3spa
dc.relation.referencesGreń, J., Gorman, I., Ruban, A., Tylš, F., Bhatt, S., & Aixalà, M. (2023). Call for Evidence-Based Psychedelic Integration. Experimental and Clinical Psychopharmacology. Advance online publication. https://doi.org/10.1037/pha0000684spa
dc.relation.referencesGriffiths, R. R., & MacLean, K. A. (2016). Efectos de los psicodélicos en la personalidad y el bienestar psicológico. Revista de Neuropsicofarmacología, 41(1), 73-82.spa
dc.relation.referencesGriffiths, R. R., Johnson, M. W., Carducci, M. A., Umbricht, A., Richards, W. A., Richards, B. D., ... & Klinedinst, M. A. (2016). Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial.spa
dc.relation.referencesGriffiths, R. R., Johnson, M. W., & Richards, W. A. (2008). Human hallucinogen research: Guidelines for safety. Journal of Psychopharmacology, 22(6), 603-620. https://doi.org/10.1177/0269881108093587spa
dc.relation.referencesGrob, C. S., Danforth, A. L., Chopra, G. S., Hagerty, M., McKay, C. R., Halberstadt, A. L., & Greer, G. R. (2011). Pilot study of psilocybin treatment for anxiety in patients with advanced-stage cancer. Archives of General Psychiatry, 68(1), 71-78. https://jamanetwork.com/journals/jamapsychiatry/fullarticle/210962spa
dc.relation.referencesGrof, S. (1980). LSD psychotherapy. Pomona, CA: Hunter House.spa
dc.relation.referencesGukasyan, N., & Nayee, S. (2022). Psilocybin for major depressive disorder: Clinical trials and perspectives. Expert Opinion on Investigational Drugs, 1-9. https://doi.org/10.1080/13543784.2022.2114772spa
dc.relation.referencesGuimarães, R. (2011). Ayahuasca: physiological and subjective effects, comparison with d-amphetamine, and repeated dose assessment [Tesis Doctoral, Universitat Autònoma de Barcelona]. Dipòsit Digital de Documents de la UAB. https://ddd.uab.cat/record/100621?ln=esspa
dc.relation.referencesHaijen, E. C. H. M., Kaelen, M., Roseman, L., Timmermann, C., Kettner, H., Dus, J., ... Carhart-Harris, R. L. (2018). Predicting responses to psychedelics: A prospective study. Frontiers in Pharmacology, 9, 897. https://doi.org/10.3389/fphar.2018.00897spa
dc.relation.referencesHausfeld, R., & Johnson, M. W. (2020). Psilocibina y trastorno de estrés postraumático: una nueva vía para la curación. Revista de Psicoterapia Experimental y Clínica, 29(2), 112-119.spa
dc.relation.referencesHernández, S., Fernández, C y Baptista, M. (2014). Metodología de la investigación. Mcgraw Hill Education.spa
dc.relation.referencesHendricks, P. S., Johnson, M. W., & Griffiths, R. R. (2014). Psilocybin, psychological distress, and suicidality. Journal of Psychopharmacology, 29(9), 1041-1043. https://doi.org/10.1177/0269881115598338spa
dc.relation.referencesHillebrand, J., Olszewski, D., & Sedefov, R. (2001). GHB and its precursor GBL: An emerging trend case study. Publications Office.spa
dc.relation.referencesHofmann, A., Heim, R., Brack, A., & Kobel, H. (1958). Psilocybin, a psychotropic substance from the Mexican mushroom Psilocybe mexicana Heim. Experientia, 14(3), 107-109.spa
dc.relation.referencesHofmann, A. (1963). The active principle of the Mexican magic mushroom: Psilocybin. Botanical Museum Leaflets, Harvard University, 20(3), 61-76.spa
dc.relation.referencesHofmann, A. (1980). LSD: My problem child. McGraw-Hill.spa
dc.relation.referencesHolas, P., Kamińska, J. Mindfulness meditation and psychedelics: potential synergies and commonalities. Pharmacol. Vol 75, 1398–1409 (2023). https://doi.org/10.1007/s43440-023-00551-8spa
dc.relation.referencesHolland, J. (Ed.). (2001). Ecstasy: The complete guide: A comprehensive look at the risks and benefits of MDMA. Inner Traditions/Bear.spa
dc.relation.referencesHoyos Botero, C. (2000). Un modelo para investigación documental. Guía teórico-práctica sobre construcción de Estados del Arte. Medellín: Señal Editora.spa
dc.relation.referencesJardim AV, Jardim DV, Chaves BR, Steglich M, Ot'alora G M, Mithoefer MC, da Silveira DX, Tófoli LF, Ribeiro S, Matthews R, Doblin R, Schenberg EE. 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for victims of sexual abuse with severe post-traumatic stress disorder: an open label pilot study in Brazil. Braz J Psychiatry. 2021 Mar-Apr;43(2):181-185. doi: 10.1590/1516-4446-2020-0980. PMID: 32638920; PMCID: PMC8023155.spa
dc.relation.referencesJohnson, M. W., Garcia-Romeu, A., & Griffiths, R. R. (2019). Potencial de los psicodélicos para el tratamiento de las adicciones. Revisiones actuales en neurociencias del comportamiento, 12(1), 116-125.spa
dc.relation.referencesJohnson, M. W., Garcia-Romeu, A., Cosimano, M. P., & Griffiths, R. R. (2014). Pilot study of the 5-HT2AR agonist psilocybin in the treatment of tobacco addiction. Journal of Psychopharmacology, 28(11), 983–992. https://doi.org/10.1177/0269881114548296spa
dc.relation.referencesJohnson, M. W., Hendricks, P. S., Barrett, F. S., & Griffiths, R. R. (2018). Classic psychedelics: An integrative review of epidemiology, therapeutics, mystical experience, and brain network function. Pharmacology & Therapeutics, 197, 83-102.spa
dc.relation.referencesJohnson, M. W., Richards, W. A., & Griffiths, R. R. (2014). Human hallucinogen research: guidelines for safety. Journal of Psychopharmacology, 28(4), 643-651.spa
dc.relation.referencesJonathan, H.; Jaime, H.; Serdar, D.; Baker, G. (2019). Ayahuasca: Psychological and Physiologic Effects, Pharmacology and Potential Uses in Addiction and Mental Illness. Current Neuropharmacology, Volume 17, Number 2, , pp. 108-128(21). https://doi.org/10.2174/1570159X16666180125095902spa
dc.relation.referencesJournal of Psychopharmacology, 30(12), 1181–1197. https://doi.org/10.1177/0269881116675513spa
dc.relation.referencesKangaslampi, S. (2023). Association between mystical-type experiences under psychedelics and improvements in well-being or mental health – A comprehensive review of the evidence. Journal of Psychedelic Studies, 7(1), 18-28. https://doi.org/10.1556/2054.2023.00243spa
dc.relation.referencesKazdin, A. E. (2015). Treatment as usual and routine care in research and clinical practice. Clinical Psychology Review, 42, 168–178. https://doi.org/10.1016/j.cpr.2015.08.008spa
dc.relation.referencesKazdin, A. E., & Rabbitt, S. M. (2013). Case study research designs. In G. J. Madden (Ed.), APA handbook of behavior analysis, Vol. 2. Translating principles into practice (pp. 307–326). American Psychological Association. https://doi.org/10.1037/13938-015spa
dc.relation.referencesKelmendi B, Kichuk SA, DePalmer G, Maloney G, Ching THW, Belser A, Pittenger C. Single-dose psilocybin for treatment-resistant obsessive-compulsive disorder: A case report. Heliyon. 2022 Dec 6;8(12):e12135. doi: 10.1016/j.heliyon.2022.e12135. PMID: 36536916; PMCID: PMC9758406.spa
dc.relation.referencesKeski-Rahkonen, A., & Mustelin, L. (2016). Epidemiology of eating disorders in Europe: Prevalence, incidence, comorbidity, course, consequences, and risk factors. Current Opinion in Psychiatry, 29(6), 340-345. https://doi.org/10.1097/YCO.0000000000000278spa
dc.relation.referencesKestel, D. (10 de octubre de 2022). Estado de la salud mental tras la pandemia del COVID-19 y progreso de la Iniciativa Especial para la Salud Mental (2019-2023) de la OMS. Crónica ONU. https://www.un.org/es/cr%C3%B3nica-onu/estado-de-la-salud-mental-tras-la-pandemia-del-covid -19-y-progreso-de-la-iniciativa#spa
dc.relation.referencesKettner H, Roseman L, Gazzaley A, Carhart-Harris RL, Pasquini L. Effects of Psychedelics in Older Adults: A Prospective Cohort Study. Am J Geriatr Psychiatry. 2024 Sep;32(9):1047-1059. doi: 10.1016/j.jagp.2024.05.007. Epub 2024 May 19. PMID: 38849218; PMCID: PMC11316630.spa
dc.relation.referencesKeup, W. (1978). Formation and transformation reactions of psilocybin and psilocin. Journal of Heterocyclic Chemistry, 15(5), 917-919.spa
dc.relation.referencesKrediet, E.; Bostoen, T.; Breeksema, J.; van Schagen, A.; Passie, T.; Vermetten, E. (2020) Reviewing the Potential of Psychedelics for the Treatment of PTSD, International Journal of Neuropsychopharmacology, Volume 23(6), Pages 385–400. https://doi.org/10.1093/ijnp/pyaa018spa
dc.relation.referencesKuypers, K. P. C., Mason, N. L., Mischler, E., & Uthaug, M. V. (2019). Sub-acute effects of psilocybin on empathy, creative thinking, and subjective well-being. Journal of Psychoactive Drugs, 51(2), 123-134. https://doi.org/10.1080/02791072.2019.1580804spa
dc.relation.referencesKwan, A.C., Olson, D.E., Preller, K.H. et al. The neural basis of psychedelic action. Nat Neurosci. Vol 25, 1407–1419 (2022). https://doi.org/10.1038/s41593-022-01177-4spa
dc.relation.referencesLabate, B. C., & Cavnar, C. (2014). The Therapeutic Use of Ayahuasca. Springer Berlin Heidelberg.spa
dc.relation.referencesLea, T., Amada, N., Jansric, M., Silva, N., & Church, J. (2020). Ensayo clínico de fase 2 de LSD en el trastorno obsesivo-compulsivo resistente al tratamiento. Revista de Psicofarmacología, 34(1), 1-12.spa
dc.relation.referencesLee, M. A., & Shlain, B. (1992). Acid dreams: The complete social history of LSD: The CIA, the Sixties, and beyond. Grove Press.spa
dc.relation.referencesLeichsenring, F., Luyten, P., Hilsenroth, M. J., Abbass, A., Barber, J. P., Keefe, J. R., ... Steinert, C. (2015). Psychodynamic therapy meets evidence-based medicine: A systematic review using updated criteria. The Lancet Psychiatry, 2(7), 648–660. https://doi.org/10.1016/S2215-0366(15)00155-8spa
dc.relation.referencesLey 23 de 1982. Sobre derechos de autor. Diario Oficial No. 35.945. Congreso de la República de Colombia, 28 de enero de 1982.spa
dc.relation.referencesLey 1090 de 2006. Por la cual se reglamenta el ejercicio de la profesión de Psicología. Diario Oficial No. 46.383. Congreso de la República de Colombia, 13 de septiembre de 2006.spa
dc.relation.referencesLiblik, S. A., Cunha, T. R., Liblik, C. S., Biscioni, D. N., & Girardi, D. R. (2024). Ética en el uso de psicodélicos: la definición de las drogas ilícitas bajo la óptica de la bioética crítica. Salud Colectiva, Vol 20, 1-9. https://doi.org/10.18294/sc.2024.4630spa
dc.relation.referencesLiechti, M. (2015). Farmacología de las sustancias eméticas de club. Neuropsicofarmacología, 40(2), 245-266.spa
dc.relation.referencesLiechti, M. E. (2015). Novel psychoactive substances (designer drugs): Overview and pharmacology of modulators of monoamine signaling. Swiss Medical Weekly, 145, w14043. https://doi.org/10.4414/smw.2015.14043spa
dc.relation.referencesLiechti, M. E. (2017). Modern clinical research on LSD. Neuropsychopharmacology, 42(11), 2114-2127. https://doi.org/10.1038/npp.2017.86spa
dc.relation.referencesLozaiga-Velder, A y Lozaiga, A. (2017). EL POTENCIAL TERAPÉUTICO DE LOS ALUCINÓGENOS EN EL TRATAMIENTO DE LAS ADICCIONES. Revista electrónica de Psicología Iztacala, 20, (3), 2017. https://www.revistas.unam.mx/index.php/repi/article/view/61747spa
dc.relation.referencesLy, C., Greb, A. C., Cameron, L. P., Wong, J. M., Barragan, E. V., Wilson, P. C., ... Duim, W. C. (2018). Psychedelics promote structural and functional neural plasticity. Cell Reports, 23(11), 3170–3182. https://doi.org/10.1016/j.celrep.2018.05.022spa
dc.relation.referencesLyon, R. A., Glennon, R. A., & Teitler, M. (1986). Arylalkylamino-and indolylalkylamino-substituted 3,4-methylenedioxyamphetamines: 3,4-methylenedioxyamphetamine analogues. Journal of Medicinal Chemistry, 29(6), 855-862. https://doi.org/10.1021/jm00156a004spa
dc.relation.referencesMaćkowiak, M. (2023). Psychedelics action and schizophrenia. Pharmacol. Rep 75, 1350–1361. https://doi.org/10.1007/s43440-023-00546-5spa
dc.relation.referencesMacLean KA, Johnson MW, Griffiths RR. Mystical experiences occasioned by the hallucinogen psilocybin lead to increases in the personality domain of openness. J Psychopharmacol. 2011 Nov;25(11):1453-61. doi: 10.1177/0269881111420188. Epub 2011 Sep 28. PMID: 21956378; PMCID: PMC3537171.spa
dc.relation.referencesMajić, T., Schmidt, T. T., & Gallinat, J. (2015). Peak experiences and the after-effects of psilocybin: A prospective study. Frontiers in Psychology, 6, 508. https://doi.org/10.3389/fpsyg.2015.00508spa
dc.relation.referencesMastinu, A.; Anyanwu, M.; Carone, M.; Abate, G.; Bonini, S.A.; Peron, G.; Tirelli, E.; Pucci, M.; Ribaudo, G.; Oselladore, E.; et al (2023). The Bright Side of Psychedelics: Latest Advances and Challenges in Neuropharmacology. Int. J. Mol. Sci. 24, (1329). https://doi.org/10.3390/ijms24021329spa
dc.relation.referencesMitchell, J. M., Bogenschutz, M., Lilientric, A., Harrison, C., Kleiman, S., Parker-Guilbert, K., ... & Doblin, R. (2021). MDMA-assisted therapy for severe PTSD: A randomized, double-blind, placebo-controlled phase 3 study. Nature Medicine, 27(6), 1025-1033. https://doi.org/10.1038/s41591-021-01336-3spa
dc.relation.referencesMithoefer, M. C., Feduccia, A. A., & Doblin, R. (2018). Terapia asistida con MDMA para el trastorno de estrés postraumático: un ensayo clínico de fase 2. Revista de Psicofarmacología, 32(1), 89-99.spa
dc.relation.referencesMithoefer, M. C., Feduccia, A. A., Jerome, L., Mithoefer, A., Wagner, M., Walsh, Z., ... Doblin, R. (2018). MDMA-assisted psychotherapy for treatment of PTSD: Study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials. Psychopharmacology, 236(9), 2735–2745. https://doi.org/10.1007/s00213-019-05249-5spa
dc.relation.referencesMithoefer, M. C., Grob, C. S., & Brewerton, T. D. (2016). Novel psychopharmacological therapies for psychiatric disorders: psilocybin and MDMA. The Lancet Psychiatry, 3(5), 481-488.spa
dc.relation.referencesMnookin S. Out of the shadows: making mental health a global development priority [Internet]. Washington, DC: Banco Mundial; 2016 [consultado el 20 de diciembre del 2021]. Disponible en: http://documents.worldbank.org/curated/en/270131468187759113/Out-of-the-shadows-making- mental-health-a-globaldevelopment-priority.spa
dc.relation.referencesMoreno, F. A., Wiegand, C. B., Taitano, E. K., & Delgado, P. L. (2006). Psilocibina, anatómicamente entrelazada vía dopamina-serotonina mediando circuitos obsesivo-compulsivos: un modelo neurobiológico. Revista de Psicofarmacología, 20(6), 1179-1183.spa
dc.relation.referencesNational Institute on Drug Abuse. (septiembre de 2017). What are the effects of MDMA. https://nida.nih.gov/publications/research-reports/mdma-ecstasy-abuse/what-are-effects-mdmaspa
dc.relation.referencesNautiyal KM, Yaden DB. Does the trip matter? Investigating the role of the subjective effects of psychedelics in persisting therapeutic effects. Neuropsychopharmacology. 2023 Jan;48(1):215-216. doi: 10.1038/s41386-022-01424-z. PMID: 35982239; PMCID: PMC9700748.spa
dc.relation.referencesNicholson, T. C., & Balster, R. L. (2001). Chemistry and synthesis of LSD and its metabolites. En B. L. Holland (Ed.), Biotransformation and metabolite elucidation of LSD (pp. 1-38). Forensic Science and Medicine.spa
dc.relation.referencesNichols, D. E. (2016). Psicodélicos. Pharmacological Reviews, 68(2), 264-355.spa
dc.relation.referencesNielson, E. M., & Guss, J. (2018). The influence of therapists' first-hand experience with psychedelics on psychedelic-assisted psychotherapy research and therapist training. Journal of Psychedelic Studies, 2(2), 64-73.spa
dc.relation.referencesNoller, G. E., Frampton, C. M., & Yazar-Klosinski, B. (2018). Ibogaina: Tratamiento para la adicción a los opioides. Revista de Medicina Psicodélica, 2(3), 230-242.spa
dc.relation.referencesNoorani, T., Siegel, N., Curtright, A., & Garcia, P. (2022). Psychedelic therapy for smoking cessation: Rationale, opportunities and challenges. Neuropharmacology, 108976. https://www.researchgate.net/publication/325967625_Psychedelic_therapy_for_smoking_cessati on_Qualitative_analysis_of_participant_accountsspa
dc.relation.referencesNutt, D. J., Erritzoe, D., & Carhart-Harris, R. (2020). Psychedelic psychiatry's brave new world. Cell, 181(1), 24–28. https://doi.org/10.1016/j.cell.2020.03.020spa
dc.relation.referencesOrganización Mundial de la Salud. (8 de junio de 2022). Trastornos mentales. https://www.who.int/es/news-room/fact-sheets/detail/mental-disordersspa
dc.relation.referencesOrganización Mundial de la Salud. Constitución de la Organización Mundial de la Salud [Internet]. Ginebra: OMS; 1946. Disponible en: https://apps.who.int/gb/bd/ pdf_files/BD_49th-sp.pdf#page=7spa
dc.relation.referencesOsório, F. L., Sanches, R. F., Macedo, L. R., Santos, R. G., Maia-de-Oliveira, J. P., Wichert-Ana, L., Araujo, D. B., Riba, J., Crippa, J. A., & Hallak, J. E. (2015). Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report. Revista Brasileira de Psiquiatria, 37(1), 13-20. https://doi.org/10.1590/1516-4446-2014-1496spa
dc.relation.referencesPalhano-Fontes, F., Barreto, D., Onias, H., Andrade, K. C., Novaes, M. M., Pessoa, J. A., ... & Araújo, D. B. (2019). Ayahuasca asistida por terapia para la depresión resistente al tratamiento: un ensayo clínico aleatorizado, doble ciego, controlado con placebo. Psychological Medicine, 49(9), 621-631.spa
dc.relation.referencesPassie, T., Halpern, J. H., Stichtenoth, D. O., Emrich, H. M., & Hintzen, A. (2008). The pharmacology of lysergic acid diethylamide: A review. CNS Neuroscience & Therapeutics, 14(4), 295-314. https://doi.org/10.1111/j.1755-5949.2008.00059.xspa
dc.relation.referencesPhelps, J. (2017). Developing guidelines and competencies for the training of psychedelic therapists. Journal of Humanistic Psychology, 57(5), 450-487.spa
dc.relation.referencesPollan, M., & Griffiths, R. R. (2018). Psicodélicos y neuroplasticidad: perspectivas y aplicaciones terapéuticas. Tendencias en Neurociencias, 41(2), 85-92.spa
dc.relation.referencesProchaska, J. O., & Norcross, J. C. (2018). Systems of psychotherapy: A transtheoretical analysis (9th ed.). Oxford University Press.spa
dc.relation.referencesPodrebarac, S. K., O'Donnell, K. C., Mennenga, S. E., Owens, L. T., Malone, T. C., Duane, J. H., & Bogenschutz, M. P. (2021). Spiritual experiences in psychedelic-assisted psychotherapy: Case reports of communion with the divine, the departed, and saints in research using psilocybin for the treatment of alcohol dependence. Spirituality in Clinical Practice, 8(3), 177–187. https://doi.org/10.1037/scp0000242spa
dc.relation.referencesPsiuk, D.; Nowak, E.M.; Dycha, N.; Łopusza ́ nska, U.; Kurzepa, J.; Samardakiewicz, M. (2022). Esketamine and Psilocybin—The Comparison of Two Mind-Altering Agents in Depression Treatment: Systematic Review. Int. J. Mol. Sci. 23, (11450). https://doi.org/10.3390/ijms231911450spa
dc.relation.referencesRätsch, C. (2005). The encyclopedia of psychoactive plants: Ethnopharmacology and its applications. Park Street Press.spa
dc.relation.referencesReiff, C. M., Richman, E. E., Nemeroff, C. B., Carpenter, L. L., Widge, A. S., Rodriguez, C. I., ... Work Group on Biomarkers and Novel Treatments, a Division of the American Psychiatric Association Council of Research. (2020). Psychedelics and psychedelic-assisted psychotherapy. American Journal of Psychiatry, 177(5), 391–410. https://doi.org/10.1176/appi.ajp.2019.19010035spa
dc.relation.referencesRiba, J., Valle, M., Urbano, G., Yritia, M., Morte, A., & Barbanoj, M. J. (2003). Human Pharmacology of Ayahuasca: Subjective and Cardiovascular Effects, Monoamine Metabolite Excretion, and Pharmacokinetics. Journal of Pharmacology and Experimental Therapeutics, 306(1), 73–83. https://doi.org/10.1124/jpet.103.049882spa
dc.relation.referencesRifkin, B. D., Maraver, M. J., & Colzato, L. S. (2020). Microdosing psychedelics as cognitive and emotional enhancers. Psychology of Consciousness: Theory, Research, and Practice, 7(3), 316–329. https://doi.org/10.1037/cns0000213spa
dc.relation.referencesRobledo, C. (2003). Técnicas y procesos de investigación.spa
dc.relation.referencesRochester, J., Vallely, A., Grof, P., Williams, M. T., Chang, H., & Caldwell, K. (2022). Entheogens and psychedelics in Canada: Proposal for a new paradigm. Canadian Psychology / Psychologie canadienne, 63(3), 413–430. https://doi.org/10.1037/cap0000285spa
dc.relation.referencesRodrigues, E., Kulić, N., & Dragičević, D. (2008). Plant sources of DMT. Biochemical Systetics and Ecology, 36(2), 73-92. https://doi.org/10.1016/j.bse.2007.09.003spa
dc.relation.referencesRoseman, L., Nutt, D. J., & Carhart-Harris, R. L. (2018). Quality of acute psychedelic experience predicts therapeutic efficacy of psilocybin for treatment-resistant depression. Frontiers in Pharmacology, 8, 974.spa
dc.relation.referencesRoss, S., Agrawal, M., Griffiths, R. R., Grob, C., Berger, A., & Henningfield, J. E. (2022). Psychedelic-assisted psychotherapy to treat psychiatric and existential distress in life-threatening medical illnesses and palliative care. Neuropharmacology, 216, 109174. https://doi.org/10.1016/j.neuropharm.2022.10917.spa
dc.relation.referencesRoss, S., Bossis, A., Guss, J., Agin-Liebes, G., Malone, T., Cohen, B., ... Schmidt, B. L. (2016). Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: A randomized controlled trial. Journal of Psychopharmacology, 30(12), 1165–1180. https://doi.org/10.1177/0269881116675512spa
dc.relation.referencesRudgley, R. (1998). The encyclopedia of psychoactive substances. Little, Brown and Company.spa
dc.relation.referencesSaeger, H. N., & Olson, D. E. (2022). Psychedelic-inspired approaches for treating neurodegenerative disorders. Journal of Neurochemistry, 162, 109–127. https://doi.org/10.1111/jnc.15544spa
dc.relation.referencesSessa, B. (2012). The psychedelic renaissance: Reassessing the role of psychedelic drugs in 21st century psychiatry and society. London: Muswell Hill Press.spa
dc.relation.referencesSessa, B., Higbed, L., & Nutt, D. (2019). A utopian solution to a uniquely modern problem? A case study of MDMA-assisted psychotherapy in the UK. The Routledge Handbook of Drug Use and Society.spa
dc.relation.referencesSchenberg, E. E. (2018). Psychedelic-assisted psychotherapy: A paradigm shift in psychiatric research and development. Frontiers in Pharmacology, 9, 733. https://doi.org/10.3389/fphar.2018.00733spa
dc.relation.referencesShulgin, A., & Shulgin, A. (1997). TIHKAL: The Continuation. Transform Press.spa
dc.relation.referencesSchlag, A.; Aday, J.; Salam, I.; Neill, J.; & Nutt, D. (2022). Adverse effects of psychedelics: From anecdotes and misinformation to systematic science. Journal of Psychopharmacology, Vol. 36(3) 258 – 272. https://doi.org/10.1177/02698811211069100spa
dc.relation.referencesSchultes, R. E., & Hofmann, A. (1979). Plants of the gods: Origins of hallucinogenic use. McGraw-Hill.spa
dc.relation.referencesSchultes, R. E., Hofmann, A., & Rätsch, C. (2001). Plants of the gods: Their sacred, healing, and hallucinogenic powers (2nd ed.). Healing Arts Press.spa
dc.relation.referencesSpriggs, M. J., Kettner, H., & Carhart-Harris, R. L. (2021). Positive effects of psychedelics on depression and wellbeing scores in individuals reporting an eating disorder. Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity, 26(4), 1265-1270. https://doi.org/10.1007/s40519-020-01000-8spa
dc.relation.referencesStamets, P. (1996). Psilocybin mushrooms of the world: An identification guide. Ten Speed Press.spa
dc.relation.referencesStevens, J. (1987). Storming heaven: LSD and the American dream. Harper & Row.spa
dc.relation.referencesStuderus, E., Kometer, M., Hasler, F., & Vollenweider, F. X. (2011). Efectos agudos, subagudos y crónicos de la psilocibina en humanos: una actualización. Perspectivas actuales en psicología, 20(4), 297-312.spa
dc.relation.referencesSwanson, R. (2018). Unifying Theories of Psychedelic Drug Effects. Volume 9 – 2018. https://doi.org/10.3389/fphar.2018.00172spa
dc.relation.referencesSwift, T. C., Belser, A. B., Agin-Liebes, G., Devenot, N., Terrana, S., Friedman, H. L., Guss, J., Bossis, A. P., & Ross, S. (2017). Cancer at the Dinner Table: Experiences of Psilocybin-Assisted Psychotherapy for the Treatment of Cancer-Related Distress. Journal of Humanistic Psychology, 57(5), 488-519. https://doi.org/10.1177/0022167817715966spa
dc.relation.referencesTimmermann, C. (2014). Neurociencias y aplicaciones psicoterapéuticas en el renacimiento de la investigación con psicodélicos. REV CHIL NEURO-PSIQUIAT 2014; 52 (2): 93-102. https://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-92272014000200005spa
dc.relation.referencesTimmermann, C., Zeifman, R.J., Erritzoe, D. et al. Effects of DMT on mental health outcomes in healthy volunteers. Sci Rep 14, 3097 (2024). https://doi.org/10.1038/s41598-024-53363-yspa
dc.relation.referencesTsang W, Ruffell SG, Netzband N, et al. Can ayahuasca reduce inattention, hyperactivity and impulsivity? A pilot study. Drug Science, Policy and Law. 2023;9. doi:10.1177/20503245231215413spa
dc.relation.referencesVan der Kolk, BA.; Wang, JB.; Yehuda, R.; Bedrosian, L.; Coker, AR.; Harrison, C.; et al. (2024). Effects of MDMA-assisted therapy for PTSD on self-experience. PLoS ONE 19(1): e0295926. https://doi.org/10.1371/journal.pone.0295926spa
dc.relation.referencesVázquez G. H., Bortolato B., Zaratiegui R., Lorenzo L. S., Aizpurua I., & Reinares M. (2021). Predictors of Recurrence in Remitted Major Depressive Disorder: A Comprehensive Literature Review. International journal of environmental research and public health, 18(3), 1083. https://doi.org/10.3390/ijerph18031083spa
dc.relation.referencesVázquez, C., Hervás, G., Rahona, J. J., & Gómez, D. (2015). Bienestar psicológico y salud: Aportaciones desde la Psicología Positiva. Anuario de Psicología Clínica y de la Salud, 5, 15–28.spa
dc.relation.referencesVermetten, E.; Krediet, E.; Bostoen, T.; Breeksema, J.J.; Schoevers, R.A.; van den Brink, W. (2020). Psychedelica bij de behandeling van PTSS. Tijdschrift voor psychiatrie. Vol 8, 640-649. https://es.wired.com/articulos/psicodelico-ibogaina-logra-disminuir-trastorno-de-estres-postraum atico-en-pacientes#:~:text=enero%20de%202024-,El%20psicod%C3%A9lico%20iboga%C3%A Dna%20logra%20disminuir%20el%20trastorno%20de%20estr%C3%A9s%20postraum%C3%A 1tico,en%20veteranos%20con%20lesiones%20cerebrales.spa
dc.relation.referencesVollenweider, F. X., & Kometer, M. (2019). Los efectos antidepresivos de los psicodélicos: ¿un nuevo mecanismo terapéutico? Revista de Psicofarmacología, 33(1), 29-37.spa
dc.relation.referencesVollenweider, F. X., & Preller, K. H. (2020). Modulación psicodélica de la actividad cerebral relacionada con la ansiedad. Revista de Neurociencia Cognitiva, 16(1), 48-58.spa
dc.relation.referencesVollenweider, F. X., & Preller, K. H. (2020). Psychedelic drugs: Neurobiology and potential for treatment of psychiatric disorders. Nature Reviews Neuroscience, 21(11), 611–624. https://doi.org/10.1038/s41583-020-0367-2spa
dc.relation.referencesWampold, B. E. (2015). How important are the common factors in psychotherapy? An update. World Psychiatry, 14(3), 270–277. https://doi.org/10.1002/wps.20238spa
dc.relation.referencesWasson, R. G. (1957). Seeking the magic mushroom. Life, 42(19), 100-120.spa
dc.relation.referencesWatts, R., Day, C., Krzanowski, J., Nutt, D., & Carhart-Harris, R. (2017). Patients' accounts of increased "connectedness" and "acceptance" after psilocybin for treatment-resistant depression. Journal of Humanistic Psychology, 57(5), 520–564. https://doi.org/10.1177/0022167817709585spa
dc.relation.referencesWeiss, B., Dinh-Williams, L.-A. L., Beller, N., Raugh, I. M., Strauss, G. P., & Campbell, W. K. (2023, diciembre 7). Ayahuasca in the Treatment of Posttraumatic Stress Disorder: Mixed-Methods Case Series Evaluation in Military Combat Veterans. Psychological Trauma: Theory, Research, Practice, and Policy. Advance online publication. https://dx.doi.org/10.1037/tra0001625spa
dc.relation.referencesWilkinson, S. T., Ballard, E. D., Bloch, M. H., Mathew, S. J., Murrough, J. W., Feder, A., ... & Zarate Jr, C. A. (2017). Un ensayo aleatorizado de psilocibina para el tratamiento del trastorno obsesivo-compulsivo. Revista de Psicofarmacología, 31(10), 1246-1254.spa
dc.relation.referencesWinkelman, M., & Sessa, B. (Eds.). (2023). Avances en la investigación de psicodélicos: Implicaciones para la conciencia, la terapia y la sociedad. Fondo de Cultura Económica.spa
dc.relation.referencesYaden, D & Griffiths, R. (2020). The Subjective Effects of Psychedelics Are Necessary for Their Enduring Therapeutic Effects. ACS Pharmacol. Transl. Sci. 2021, 4, 2, 568–572 https://doi.org/10.1021/acsptsci.0c00194spa
dc.relation.referencesYaden, D.; Johnson, M.; Griffiths, R.; Doss, M.; Garcia-Romeu, A.; Nayak, S.; Gukasyan, N.; Mathur, B.; Barrett, F. (2021). Psychedelics and Consciousness: Distinctions, Demarcations, and Opportunities. International Journal of Neuropsychopharmacology, Volume 24, Issue 8. Pages 615–623. https://doi.org/10.1093/ijnp/pyab026.spa
dc.relation.uriapolohttps://apolo.unab.edu.co/en/persons/martha-eugenia-ortega-ortizspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.creativecommonsAtribución-NoComercial-SinDerivadas 2.5 Colombia*
dc.rights.localAbierto (Texto Completo)spa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/*
dc.subject.keywordsPsychedelicsspa
dc.subject.keywordsPsychotherapyspa
dc.subject.keywordsDocumentary reviewspa
dc.subject.keywordsMystical experiencesspa
dc.subject.keywordsAyahuascaspa
dc.subject.keywordsPsilocybinspa
dc.subject.keywordsKetaminespa
dc.subject.keywordsTreatmentspa
dc.subject.keywordsMental disordersspa
dc.subject.keywordsProtocolsspa
dc.subject.keywordsPsychologyspa
dc.subject.keywordsPersonality disordersspa
dc.subject.keywordsMental healthspa
dc.subject.keywordsNeurobehavioral disordersspa
dc.subject.keywordsAnxietyspa
dc.subject.keywordsDepression, Mental (Prevention)spa
dc.subject.lembPsicologíaspa
dc.subject.lembTrastornos de la personalidadspa
dc.subject.lembSalud mentalspa
dc.subject.lembTrastornos neuroconductualesspa
dc.subject.lembAnsiedadspa
dc.subject.lembDepresión mental (Prevención)spa
dc.subject.proposalPsicodélicosspa
dc.subject.proposalPsicoterapiaspa
dc.subject.proposalRevisión documentalspa
dc.subject.proposalExperiencias místicasspa
dc.subject.proposalLSDspa
dc.subject.proposalMDMAspa
dc.subject.proposalAyahuascaspa
dc.subject.proposalPsilocibinaspa
dc.subject.proposalDMTspa
dc.subject.proposalKetaminaspa
dc.subject.proposalTratamientospa
dc.subject.proposalTrastornos mentalesspa
dc.subject.proposalProtocolosspa
dc.titleRevisión documental sobre el uso de sustancias psicodélicas en la psicoterapiaspa
dc.title.translatedDocumentary review on the use of psychedelic substances in psychotherapyspa
dc.type.coarhttp://purl.org/coar/resource_type/c_7a1f
dc.type.coarversionhttp://purl.org/coar/version/c_ab4af688f83e57aaspa
dc.type.driverinfo:eu-repo/semantics/bachelorThesis
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersion
dc.type.localTrabajo de Gradospa
dc.type.redcolhttp://purl.org/redcol/resource_type/TP

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