Incidencia de endoftalmitis aguda postoperatoria después de facoemulsificación, efecto de la moxifloxacina intracameral : estudio de cohorte 2007-2011

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dc.contributor.advisorTello Hernández, Alejandrospa
dc.contributor.authorSánchez Uzcátegui, Mary Alejandraspa
dc.contributor.cvlachttps://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001009125*
dc.contributor.googlescholarhttps://scholar.google.es/citations?hl=es#user=puxZHKYAAAAJ*
dc.contributor.scopushttps://www.scopus.com/authid/detail.uri?authorId=6603664598*
dc.coverageBucaramanga (Colombia)spa
dc.coverage.campusUNAB Campus Bucaramangaspa
dc.coverage.temporal2007-2011spa
dc.date.accessioned2020-06-26T20:01:39Z
dc.date.available2020-06-26T20:01:39Z
dc.date.issued2014
dc.degree.nameEspecialista en Oftalmologíaspa
dc.description.abstractLa endoftalmitis es una complicación muy poco frecuente de la cirugía de catarata. La incidencia publicada tiene un rango gigantesco, de casi 60 veces menos en unos grupos que en otros (entre el 0,01% y 0,59%)(1-9). Puede llevar a una pérdida visual severa con agudezas visuales de 20/200 o peores en el 15-30% de los casos (10). Se han adoptado diversas medidas profilácticas para disminuir la incidencia de endoftalmitis después de cirugía de catarata. Algunas como la aplicación de iodopovidona al 0.5 % en la superficie ocular ya han demostrado su eficacia (7,8). Por otra parte el empleo de antibióticos tópicos profilácticos al igual que antibióticos en la solución de irrigación todavía es motivo de controversia, por lo que no existe un criterio unificado. En cuanto a antibióticos intraoculares, en 2007 the European Society of Cataract and Refractive Surgeons ( ESCRS) publicó un gran ensayo clínico multicéntrico incluyendo 13.698 casos, mostrando una incidencia de endoftalmitis post-operatoria en los pacientes que recibieron cefuroxima intracameral de 0.07%, comparados con el grupo control (aquellos a quienes no se les aplicó) de 0.34%, lo cual apoyaría el uso profiláctico de antibiótico en cámara anterior (11). Esto ha despertado de nuevo una vieja discusión acerca de la inyección intraocular profiláctica de antibióticos. Esta vía es muy llamativa por las altas concentraciones que se pueden alcanzar intraocularmente, pero se debe tener muy en cuenta que por efectos de toxicidad se pueden lesionar tejidos muy vulnerables como el endotelio corneal o la retina. En 2010 Garcia- Saenz y colaboradores realizaron un estudio prospectivo de la incidencia de endoftalmitis a 10 años (1999- 2008) en pacientes operados de catarata incluyendo13.652 pacientes divididos en dos grupos dependiendo de si habían recibido o no el antibiótico intracameral: la incidencia de endoftalmitis dentro de los pacientes que no recibieron cefuroxima intracameral fue del 0.590% y en quienes recibieron cefuroxima intracameral fue mucho menor (0.043%) (5).spa
dc.description.abstractenglishEndophthalmitis is a very rare complication of cataract surgery. The published incidence has a gigantic range, almost 60 times less in some groups than in others (between 0.01% and 0.59%) (1-9). It can lead to severe visual loss with visual acuities of 20/200 or worse in 15-30% of cases (10). Various prophylactic measures have been taken to decrease the incidence of endophthalmitis after cataract surgery. Some, such as the application of 0.5% povidone iodine on the ocular surface, have already demonstrated its efficacy (7,8). On the other hand, the use of prophylactic topical antibiotics as well as antibiotics in the irrigation solution is still controversial, so there is no unified criterion. Regarding intraocular antibiotics, in 2007 the European Society of Cataract and Refractive Surgeons (ESCRS) published a large multicenter clinical trial including 13,698 cases, showing an incidence of postoperative endophthalmitis in patients who received intracameral cefuroxime of 0.07%, compared to the control group (those to whom it was not applied) of 0.34%, which would support the prophylactic use of antibiotics in the anterior chamber (11). This has once again sparked an old discussion about prophylactic intraocular injection of antibiotics. This pathway is very striking due to the high concentrations that can be reached intraocularly, but it must be taken into account that due to toxicity effects, very vulnerable tissues such as the corneal endothelium or the retina can be injured. In 2010, Garcia-Saenz et al. Carried out a prospective study of the incidence of endophthalmitis at 10 years (1999-2008) in patients operated on for cataract, including 13,652 patients divided into two groups depending on whether or not they had received the intracameral antibiotic: the incidence Endophthalmitis among patients who did not receive intracameral cefuroxime was 0.590% and in those who received intracameral cefuroxime it was much lower (0.043%) (5).eng
dc.description.degreelevelEspecializaciónspa
dc.description.learningmodalityModalidad Presencialspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.instnameinstname:Universidad Autónoma de Bucaramanga - UNABspa
dc.identifier.reponamereponame:Repositorio Institucional UNABspa
dc.identifier.urihttp://hdl.handle.net/20.500.12749/1774
dc.language.isospaspa
dc.publisher.facultyFacultad Ciencias de la Saludspa
dc.publisher.grantorUniversidad Autónoma de Bucaramanga UNABspa
dc.publisher.programEspecialización en Oftalmologíaspa
dc.relation.referencesSánchez Uzcátegui, Mary Alejandra (2014). Incidencia de endoftalmitis aguda postoperatoria después de facoemulsificación, efecto de la moxifloxacina intracameral : Estudio de cohorte 2007-2011. Bucaramanga (Colombia) : Universidad Autónoma de Bucaramanga UNABspa
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dc.relation.references18- Arshinoff SA. ‘‘Advantages and Use of Intracameral Moxifloxacin for Bacterial Prophylaxis in Cataract Surgery,’’ poster presentado en la Reunión de la ASCRS Symposium on Cataract, IOL and Refractive Surgery, San Diego, Estados Unidos, 2007.spa
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dc.relation.references23-Royal College of Ophthalmologists. Cataract Surgery Guidelines. London, UK, The Royal College, Septiembre 2010. Disponible en: www.rcophth.ac.uk. Consultado el 7 de Julio de 2012, 8:24 am.spa
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dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2spa
dc.rights.creativecommonsAtribución-NoComercial-SinDerivadas 2.5 Colombia*
dc.rights.localAbierto (Texto Completo)spa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/*
dc.subject.keywordsEndophthalmitiseng
dc.subject.keywordsEye surgeryeng
dc.subject.keywordsWaterfalleng
dc.subject.keywordsMedicineeng
dc.subject.keywordsOphthalmologyeng
dc.subject.keywordsResearcheng
dc.subject.keywordsVisual acuityeng
dc.subject.keywordsIntraocular antibioticseng
dc.subject.lembEndoftalmitisspa
dc.subject.lembCirugía de los ojosspa
dc.subject.lembCatarataspa
dc.subject.lembMedicinaspa
dc.subject.lembOftalmologíaspa
dc.subject.lembInvestigacionesspa
dc.subject.proposalAgudeza visual
dc.subject.proposalAntibióticos intraoculares
dc.titleIncidencia de endoftalmitis aguda postoperatoria después de facoemulsificación, efecto de la moxifloxacina intracameral : estudio de cohorte 2007-2011spa
dc.title.translatedIncidence of postoperative acute endophthalmitis after phacoemulsification, effect of intracameral moxifloxacin: 2007-2011 cohort studyeng
dc.type.coarhttp://purl.org/coar/resource_type/c_bdcc
dc.type.driverinfo:eu-repo/semantics/masterThesis
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersion
dc.type.localTesisspa
dc.type.redcolhttp://purl.org/redcol/resource_type/TM

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