Eficacia y seguridad del manejo endovascular de pacientes con síndrome de vena cava superior

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dc.contributor.advisorGalvis Mendez, Melquizidel
dc.contributor.advisorUribe Caputti, Juan Carlos
dc.contributor.authorRomero Socarras, Rubby Esther
dc.contributor.orcidUribe Caputti, Juan Carlos [0000-0002-6602-1045]spa
dc.contributor.researchgroupGrupo de Investigaciones Clínicasspa
dc.coverage.campusUNAB Campus Bucaramangaspa
dc.coverage.spatialFloridablanca (Santander, Colombia)spa
dc.coverage.temporal2014-2024spa
dc.date.accessioned2026-02-16T13:35:45Z
dc.date.available2026-02-16T13:35:45Z
dc.date.issued2025-11-20
dc.degree.nameEspecialistas en Radiología e Imágenes Diagnósticasspa
dc.description.abstractEvaluar la eficacia y seguridad del tratamiento endovascular mediante angioplastia con y sin colocación de stent en la obstrucción de la vena cava superior. Metodología: Estudio observacional, analítico y de evaluación de impacto en pacientes diagnosticados con síndrome de vena cava superior manejados con técnicas endovasculares entre 2014 y 2024. Resultados: Se incluyeron 57 pacientes: 35 (61,4%) tratados con angioplastia sola y 22 (38,6%) con stent inicial. La permeabilidad primaria fue del 79,4% en el grupo de angioplastia sola y del 100% en el grupo con stent, diferencia estadísticamente significativa (p=0,025). La permeabilidad secundaria alcanzó el 100% en ambos grupos. Durante el seguimiento a 12 meses, la tasa de reintervención en el grupo de angioplastia sola fue del 22,8%; de estos, el 33% culminó con colocación diferida de stent. Las complicaciones menores ocurrieron en el 12,5% de los casos, siendo el hematoma en el sitio de punción la más frecuente. La mortalidad fue del 3,5%, asociada a ruptura de la vena cava superior. Conclusiones: El manejo endovascular del síndrome de vena cava superior demostró ser una estrategia segura y eficaz, con alta tasa de mejoría clínica, baja mortalidad y resultados favorables en permeabilidad primaria y secundaria, especialmente cuando se realiza la colocación temprana de stent.spa
dc.description.abstractenglishTo evaluate the efficacy and safety of endovascular treatment with angioplasty, with or without stent placement, in patients with superior vena cava obstruction. Methods: Observational, analytical, and impact evaluation study of patients diagnosed with superior vena cava syndrome who underwent endovascular management between 2014 and 2024. Results: A total of 57 patients were included: 35 (61.4%) treated with angioplasty alone and 22 (38.6%) with primary stent placement. Primary patency was 79.4% in the angioplasty group and 100% in the stent group, a statistically significant difference (p=0.025). Secondary patency reached 100% in both groups. At 12-month follow-up, the reintervention rate in the angioplasty group was 22.8%; of these, 33% ultimately required deferred stent placement. Minor complications occurred in 12.5% of cases, with puncture-site hematoma being the most frequent. Mortality was 3.5%, associated with rupture of the superior vena cava. Conclusions: Endovascular management of superior vena cava syndrome proved to be a safe and effective strategy, with high rates of clinical improvement, low mortality, and favorable primary and secondary patency outcomes, particularly when early stent placement was performed.spa
dc.description.degreelevelEspecializaciónspa
dc.description.learningmodalityModalidad Presencialspa
dc.description.tableofcontents1. INTRODUCCIÓN 4 2. PLANTEAMIENTO DEL PROBLEMA……………………………………………………..5 2.1 JUSTIFICACIÒN ……………………………………………………………………..5 3. MARCO TEÓRICO ……………………………………………………………………………7 3.1 ANATOMIA DE LA VCS, FUNCIÓN Y VARIANTES ANATÓMICAS………..7 3.2 CAUSAS DE OBSTRUCCIÓN DE LA VCS ………………………………………8 3.3 CUADRO CLINICO…………………………………………………………………9 3.4 DIAGNÓSTICO……………………………………………………………………..10 3.5 TRATAMIENTO ………………………….………………………………..............10 3.6 IMPACTO EN COLOMBIA ……………….……………………………………...14 4. ESTADO DEL ARTE ………………………………………………………………………...15 5. OBJETIVOS …………………………………………………………………………………..19 6. METODOLOGÍA ……………………………………………………………………………..20 7 ALMACENAMIENTO ELECTRÓNICO DE LA INFORMACIÓN ………………….…..21 8. DISPOSICIONES VIGENTES…………………………………………………….................22 8.1 CONSIDERACIONES ÉTICAS…………………………………………………....23 8.2. PROTECCIÓN DE DATOS PERSONALES……………………………………..24 9 RECURSOS HUMANOS, MATERIALES Y FINANCIEROS……………………………..25 RECURSOS HUMANOS……………………………………………………………….25 RECURSOS MATERIALES………………………………………………..………….25 RECURSOS FINANCIEROS…………………………………………………………..25 10. RESULTADOS………………………………………………………………………………26 11. DISCUSIÓN………………………………………………………………………………..…33 12. CONCLUSIÓN…………………………………………………………………………….... 36 13 . BIBLIOGRAFÍA………………………………………………………………………….… 37 ANEXOS ………………………………………………………………………………………… 44spa
dc.format.mimetypeapplication/pdfspa
dc.identifier.instnameinstname:Universidad Autónoma de Bucaramanga - UNABspa
dc.identifier.reponamereponame:Repositorio Institucional UNABspa
dc.identifier.repourlrepourl:https://repository.unab.edu.cospa
dc.identifier.urihttp://hdl.handle.net/20.500.12749/32875
dc.language.isospaspa
dc.publisher.facultyFacultad Ciencias de la Saludspa
dc.publisher.grantorUniversidad Autónoma de Bucaramanga UNABspa
dc.publisher.programEspecialización en Radiología e Imágenes Diagnósticasspa
dc.publisher.programidERAD-272
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dc.rights.accessrightsinfo:eu-repo/semantics/restrictedAccessspa
dc.rights.creativecommonsAtribución-NoComercial-SinDerivadas 2.5 Colombia*
dc.rights.localAbierto (Texto Completo)spa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/*
dc.subject.keywordsMedical sciencesspa
dc.subject.keywordsHealth sciencesspa
dc.subject.keywordsRadiologyspa
dc.subject.keywordsDiagnostic imagingspa
dc.subject.keywordsSuperior vena cava syndromespa
dc.subject.keywordsEndovascular procedurespa
dc.subject.keywordsPrimary patencyspa
dc.subject.keywordsReinterventionspa
dc.subject.keywordsInterventional radiologyspa
dc.subject.keywordsVenae cavaespa
dc.subject.keywordsPulmones (Cáncer)spa
dc.subject.keywordsBlood-vessels (Diseases)spa
dc.subject.lembCiencias médicasspa
dc.subject.lembRadiologíaspa
dc.subject.lembDiagnóstico para imágenesspa
dc.subject.lembVena cavaspa
dc.subject.lembLungs (Cancer)spa
dc.subject.lembVasos sanguíneos (Enfermedades)spa
dc.subject.proposalSíndrome de vena cava superiorspa
dc.subject.proposalProcedimiento endovascularspa
dc.subject.proposalStent venosospa
dc.subject.proposalPermeabilidad primariaspa
dc.subject.proposalReintervenciónspa
dc.subject.proposalRadiología intervencionistaspa
dc.subject.proposalEndovascular procedurespa
dc.titleEficacia y seguridad del manejo endovascular de pacientes con síndrome de vena cava superiorspa
dc.title.translatedEfficacy and Safety of Endovascular Treatment in Patients with Superior Vena Cava Syndromespa
dc.type.coarhttp://purl.org/coar/resource_type/c_bdcc
dc.type.coarversionhttp://purl.org/coar/version/c_ab4af688f83e57aaspa
dc.type.driverinfo:eu-repo/semantics/masterThesis
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersion
dc.type.localTesisspa
dc.type.redcolhttp://purl.org/redcol/resource_type/TM

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